Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7481567 | 0.93 | FFAR1 (0.45) | FFAR1NPC1RAB9APARP1FFAR4 | |
| SCHEMBL7435979 | 0.92 | CPT1A (0.43) | CPT1AFFAR1NPC1RAB9ARXRA | |
| SCHEMBL7487553 | 0.92 | FFAR1 (0.42) | CPT1AFFAR1NPC1RAB9ARXRA | |
| SCHEMBL7433078 | 0.92 | FFAR1 (0.42) | CPT1AFFAR1NPC1RAB9ARXRA | |
| SCHEMBL7433472 | 0.92 | CPT1A (0.42) | CPT1AFFAR1RXRARXRBRXRG | |
| SCHEMBL7434473 | 0.88 | NPC1 (0.45) | CPT1AFFAR1NPC1RAB9APARP1 | |
| SCHEMBL7488778 | 0.87 | FFAR1 (0.47) | FFAR1NPC1RAB9AFFAR4 | |
| SCHEMBL7427523 | 0.86 | NPC1 (0.49) | CPT1AFFAR1NPC1RAB9AFFAR4 | |
| SCHEMBL7484778 | 0.86 | FFAR1 (0.45) | CPT1AFFAR1NPC1RAB9AFFAR4 | |
| SCHEMBL7427408 | 0.86 | HRH3 (0.46) | CPT1AFFAR1NPC1RAB9ACPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244656-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | Pfizer Products Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001051487-A1 | NON-PEPTIDYL INHIBITORS OF VLA-4 DEPENDENT CELL BINDING USEFUL IN TREATING INFLAMMATORY, AUTOIMMUNE, AND RESPIRATORY DISEASES | PFIZER PRODUCTS INC. (US) | 2001-07-19 | — | — | WO | disclosed |