SCHEMBL7542975

SCHEMBL7542975

CCN=C=NCCCN(C)C.COCCc1nc2c(N)nc3ccccc3c2n1CCCCc1c(-c2ccccc2)nc2ccccc2c1C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3869671 0.87 TLR7 (0.52) TLR7
SCHEMBL7542973 0.79 TLR7 (0.45) TLR7
SCHEMBL5746459 0.73 TLR7 (0.53) TLR7
SCHEMBL5749579 0.73 TLR7 (0.53) TLR7
SCHEMBL5747599 0.72 TLR7 (0.60) TLR7
SCHEMBL5750984 0.72 TLR7 (0.61) TLR7
SCHEMBL5777827 0.72 TLR7 (0.55) TLR7
SCHEMBL3863646 0.72 TLR7 (0.57) TLR7
SCHEMBL1950333 0.72 TLR7 (0.62) TLR7
SCHEMBL28418118 0.71 TLR7 (0.60) TLR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187613-A4 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2002-07-24 EP disclosed
EP-1187613-A1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-03-20 EP disclosed
WO-2000076505-A1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed