Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591860 | 0.85 | FFAR1 (0.61) | FFAR1PPARD | |
| SCHEMBL7564649 | 0.83 | MAOB (0.45) | FFAR4PTGS1PTGS2MAOBALDH1A1 | |
| SCHEMBL5377290 | 0.81 | FFAR1 (0.50) | FFAR1FFAR4PPARDALDH1A1HRH3 | |
| SCHEMBL5381740 | 0.79 | PPARD (0.43) | FFAR1FFAR4PTGS1PTGS2PPARD | |
| SCHEMBL7567690 | 0.74 | CYP19A1 (0.51) | PTGS1PTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL4517358 | 0.71 | FFAR1 (0.64) | FFAR1FFAR4PTGS1PTGS2MAOB | |
| SCHEMBL5378962 | 0.71 | KMT2A (0.64) | FFAR1PTGS1PTGS2ALDH1A1L3MBTL1 | |
| SCHEMBL1068959 | 0.71 | MAOB (0.70) | FFAR1FFAR4PTGS1PTGS2MAOB | |
| SCHEMBL5377099 | 0.70 | FFAR1 (0.56) | FFAR1FFAR4PPARDALDH1A1AKR1B1 | |
| SCHEMBL5372077 | 0.70 | CYP19A1 (0.48) | PTGS1PTGS2MAOBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |