SCHEMBL7543032

SCHEMBL7543032

c1cnc2c(c1)NN=NN2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.41
CYP1A2 P05177 2/20 0.41
GSK3B P49841 1/20 0.39
AKT1 P31749 1/20 0.35
KDM4E B2RXH2 5/20 0.33
MAPT P10636 5/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
TDP1 Q9NUW8 2/20 0.32
CYP3A4 P08684 2/20 0.32
ALOX15 P16050 2/20 0.32
TSHR P16473 2/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MMP2 P08253 1/20 0.32
CYP2D6 P10635 1/20 0.32
MMP9 P14780 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7476995 0.72 SMN1; SMN2 (0.55) SMN1; SMN2CYP1A2GSK3BAKT1KDM4E
SCHEMBL7102226 0.72
SCHEMBL8103221 0.70 GSK3B (0.50) SMN1; SMN2CYP1A2GSK3BAKT1KDM4E
SCHEMBL136053 0.70 NOX1 (0.38) CYP1A2MAPTGAATDP1CYP3A4
SCHEMBL15326919 0.67 GSK3B (0.47) SMN1; SMN2CYP1A2GSK3BAKT1KDM4E
SCHEMBL458916 0.67
SCHEMBL187515 0.67
SCHEMBL15230088 0.67
SCHEMBL516458 0.67 SMN1; SMN2 (0.41) SMN1; SMN2CYP1A2GSK3BKDM4EMAPT
SCHEMBL6787340 0.67 SMN1; SMN2 (0.41) SMN1; SMN2CYP1A2GSK3BAKT1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524637-B1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK CO (US) 1996-03-06 EP claimed
EP-0524637-A1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1993-01-27 EP claimed
US-5177052-A MIXTURE OF DYES FOR CYAN DYE DONOR FOR THERMAL COLOR PROOFING EASTMAN KODAK COMPANY (US) 1993-01-05 US claimed
EP-0771672-B1 Laser recording method EASTMAN KODAK CO (US) 2002-05-15 EP disclosed
EP-0439585-B1 IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS MAG GEORG MAYRHOFER & CO OHG (AT) 1997-10-29 EP disclosed
US-5674661-A IMAGEWISE LASER EXPOSURE OF SINGLE SHEET RECORDING ELEMENT HAVING CRYSTALLIZATION RESISTANT DISAZO CYAN DYE DISPERSED IN POLYMERIC BINDER EASTMAN KODAK COMPANY (US) 1997-10-07 US disclosed
EP-0771672-A2 Laser recording element EASTMAN KODAK COMPANY (US) 1997-05-07 EP disclosed
EP-0636492-B1 Use of mixture of dyes for black laser ablative recording element EASTMAN KODAK CO (US) 1997-03-26 EP disclosed
US-5503956-A DISPERSING AN INFRARED-ABSORBING MIXTURE OF AT LEAST ONE CYAN, MAGENTA AND YELLOW DYE IN POLYMERIC BINDER EASTMAN KODAK COMPANY (US) 1996-04-02 US disclosed
EP-0524637-B1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK CO (US) 1996-03-06 EP disclosed
EP-0511625-B1 Mixture of yellow and cyan dyes to form a green hue for color filter array element EASTMAN KODAK CO (US) 1995-10-11 EP disclosed
EP-0524637-A1 Mixture of dyes for cyan dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1993-01-27 EP disclosed
US-5177052-A MIXTURE OF DYES FOR CYAN DYE DONOR FOR THERMAL COLOR PROOFING EASTMAN KODAK COMPANY (US) 1993-01-05 US disclosed
EP-0518349-A1 Mixture of cyan and yellow dyes to form a green hue for color filter array element EASTMAN KODAK COMPANY (US) 1992-12-16 EP disclosed
US-5168094-A Thermal printing EASTMAN KODAK COMPANY (US) 1992-12-01 US disclosed
EP-0511625-A1 Mixture of yellow and cyan dyes to form a green hue for color filter array element EASTMAN KODAK COMPANY (US) 1992-11-04 EP disclosed
EP-0486995-A1 Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-27 EP disclosed
EP-0483800-A1 Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1992-05-06 EP disclosed
US-5061676-A Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1991-10-29 US disclosed
US-5023229-A Mixture of dyes for magenta dye donor for thermal color proofing EASTMAN KODAK COMPANY (US) 1991-06-11 US disclosed