Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | BCHE | P06276 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.66 |
| ▸ | RELA | Q04206 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.62 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.62 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.59 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543053 | 1.00 | CYP3A4 (0.66) | CYP3A4BCHENFKB1NFKB2RELA | |
| SCHEMBL10867827 | 0.94 | CYP1B1 (0.66) | CYP3A4BCHENFKB1NFKB2RELA | |
| SCHEMBL38652058 | 0.92 | F3 (0.63) | CYP3A4BCHENFKB1NFKB2RELA | |
| SCHEMBL20828533 | 0.92 | F3 (0.63) | CYP3A4BCHENFKB1NFKB2RELA | |
| SCHEMBL13840001 | 0.88 | BCHE (0.52) | CYP3A4BCHENFKB1NFKB2RELA | |
| SCHEMBL16174211 | 0.86 | CYP3A4 (0.71) | CYP3A4BCHENFKB1NFKB2RELA | |
| SCHEMBL8964970 | 0.85 | MAOB (0.69) | CYP3A4BCHEMAPTMAOBLMNA | |
| SCHEMBL8964978 | 0.85 | MAOB (0.69) | CYP3A4BCHEMAPTMAOBLMNA | |
| SCHEMBL5068764 | 0.84 | KMT2A (0.71) | NFKB1NFKB2RELAMAPTMAOB | |
| SCHEMBL5068765 | 0.84 | KMT2A (0.71) | NFKB1NFKB2RELAMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718694-B1 | Radiation-curable composition | JAPAN SYNTHETIC RUBBER CO LTD (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-0718694-A2 | Radiation-curable composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |