Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5385710 | 0.87 | DGAT1 (0.36) | CYP4F2CYP4A11LMNAPTGDR2DGAT1 | |
| SCHEMBL7543721 | 0.86 | DGAT1 (0.36) | CYP4F2CYP4A11LMNADGAT1POLB | |
| SCHEMBL5376441 | 0.79 | FFAR4 (0.42) | PTGDR2DGAT1FFAR1L3MBTL1FFAR4 | |
| SCHEMBL6035855 | 0.79 | CYP4F2 (0.49) | CYP4F2CYP4A11LMNADGAT1ALDH1A1 | |
| SCHEMBL5385713 | 0.78 | CYP4F2 (0.34) | CYP4F2CYP4A11LMNAPOLBCACNA1G | |
| SCHEMBL5373814 | 0.78 | CYP4F2 (0.50) | CYP4F2CYP4A11LMNACACNA1GCACNA1H | |
| SCHEMBL5397402 | 0.78 | FFAR1 (0.41) | LMNAPOLBFFAR1P2RX3L3MBTL1 | |
| SCHEMBL5377167 | 0.78 | KDM4E (0.45) | CYP4F2CYP4A11LMNAALDH1A1 | |
| SCHEMBL5374629 | 0.76 | PPARG (0.46) | CYP4F2CYP4A11LMNAPTGDR2FFAR1 | |
| SCHEMBL5382748 | 0.76 | HDAC1 (0.41) | PTGDR2DGAT1FFAR1ALDH1A1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |