Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054058 | 0.91 | TSHR (0.68) | TSHRALDH1A1TP53SMN1; SMN2MEN1 | |
| SCHEMBL14725040 | 0.86 | TSHR (0.61) | TSHRALDH1A1TP53SMN1; SMN2MEN1 | |
| SCHEMBL7774828 | 0.86 | LMNA (0.65) | TSHRSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL8057246 | 0.86 | TSHR (0.64) | TSHRALDH1A1TP53SMN1; SMN2MEN1 | |
| SCHEMBL8962400 | 0.83 | GBA1 (0.60) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30784991 | 0.80 | KDM4E (0.54) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL30740023 | 0.80 | HTT (0.56) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8885835 | 0.78 | TSHR (0.69) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9913727 | 0.77 | LMNA (0.75) | TSHRALDH1A1TP53SMN1; SMN2MEN1 | |
| SCHEMBL11931979 | 0.77 | TLR8 (0.59) | TSHRALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711760-B1 | METHOD OF ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-6130332-A | USING A GROUP 8 METAL CATALYST AND ALDEHYDES OR KETONE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-10-10 | — | — | US | disclosed |
| US-5792867-A | Method of alkylating of triazine derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-11 | — | — | US | disclosed |
| EP-0760369-A1 | PROCESS FOR ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0711760-A1 | METHOD OF ALKYLATING TRIAZINE DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |