Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543911 | 1.00 | CCR5 (0.81) | CCR5KCNH2 | |
| SCHEMBL7552645 | 0.96 | CCR5 (0.75) | CCR5KCNH2 | |
| SCHEMBL7552641 | 0.96 | CCR5 (0.75) | CCR5KCNH2 | |
| SCHEMBL7546833 | 0.93 | CCR5 (0.69) | CCR5KCNH2 | |
| SCHEMBL7546829 | 0.93 | CCR5 (0.69) | CCR5KCNH2 | |
| SCHEMBL7545760 | 0.93 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL7545764 | 0.93 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL7545680 | 0.92 | CCR5 (0.86) | CCR5KCNH2 | |
| SCHEMBL7551381 | 0.92 | CCR5 (0.86) | CCR5KCNH2 | |
| SCHEMBL7549339 | 0.89 | CCR5 (1.00) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171122-A4 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO INC (US) | 2002-05-29 | — | — | EP | disclosed |
| EP-1171122-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Merck & Co., Inc. (US) | 2002-01-16 | — | — | EP | disclosed |
| US-6248755-B1 | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES | MERCK & CO., INC. | 2001-06-19 | — | — | US | disclosed |
| WO-2000059502-A1 | PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 2000-10-12 | — | — | WO | disclosed |