Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.85 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyl Alcohol SCHEMBL1483315 | 1.00 | — | — | |
| Butyl Alcohol SCHEMBL396093 | 0.96 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| Butyl Alcohol SCHEMBL9326243 | 0.96 | ALDH1A1 (0.92) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| Butyl Alcohol SCHEMBL22289700 | 0.96 | ALDH1A1 (0.92) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| Butyl Alcohol SCHEMBL29791560 | 0.96 | ALDH1A1 (0.92) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| Butyl Alcohol SCHEMBL92734 | 0.96 | — | — | |
| Butyl Alcohol SCHEMBL9227438 | 0.96 | ALDH1A1 (0.92) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| Butyl Alcohol SCHEMBL7212630 | 0.96 | ALDH1A1 (0.92) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 | |
| Butyl Alcohol SCHEMBL561265 | 0.96 | — | — | |
| Butyl Alcohol SCHEMBL4295139 | 0.92 | ALDH1A1 (0.85) | ALDH1A1SMN1; SMN2TSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005321-B1 | HAIR CONDITIONER AND 2-IN-1 CONDITIONING SHAMPOO | AKZO NOBEL NV (NL) | 2002-05-22 | — | — | EP | disclosed |
| US-6264931-B1 | REACTION PRODUCT OF ALKANOLAMINE, FATTY ACID OR FATTY ESTER AND ALKYLATION AGENT; MIXTURE WITH ANIONIC SURFACTANT | AKZO NOBEL NV. (NL) | 2001-07-24 | — | — | US | disclosed |
| EP-1005321-A2 | HAIR CONDITIONER AND 2-IN-1 CONDITIONING SHAMPOO | Akzo Nobel N.V. (NL) | 2000-06-07 | — | — | EP | disclosed |
| US-5939059-A | Hair conditioner and 2 in 1 conditioning shampoo | AKZO NOBEL NV (NL) | 1999-08-17 | — | — | US | disclosed |
| WO-1999008648-A2 | HAIR CONDITIONER AND 2-IN-1 CONDITIONING SHAMPOO | AKZO NOBEL N.V. (NL) | 1999-02-25 | — | — | WO | disclosed |