Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7225086 | 1.00 | ESR1 (0.37) | ESR1ESR2EBPSIGMAR1HSP90AA1 | |
| SCHEMBL7105874 | 0.81 | ESR1 (0.44) | ESR1ESR2EBPSIGMAR1PTGER1 | |
| SCHEMBL7111025 | 0.81 | ESR1 (0.47) | ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL7111478 | 0.80 | ESR1 (0.45) | ESR1ESR2PTGER1 | |
| SCHEMBL7109898 | 0.80 | ESR1 (0.51) | ESR1ESR2EBPSIGMAR1 | |
| SCHEMBL7112981 | 0.78 | ESR1 (0.47) | ESR1ESR2EBPSIGMAR1PTGER1 | |
| SCHEMBL7110416 | 0.78 | ESR1 (0.51) | ESR1ESR2EBPSIGMAR1FFAR4 | |
| SCHEMBL7106880 | 0.77 | ESR1 (0.51) | ESR1ESR2EBPSIGMAR1FFAR4 | |
| SCHEMBL7107864 | 0.73 | ALDH1A1 (0.40) | ESR1ESR2PTGER1 | |
| SCHEMBL3861641 | 0.72 | ESR1 (0.55) | ESR1ESR2EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826670-B1 | Naphthalene compounds, intermediates, formulations, and methods | LILLY CO ELI (US) | 2002-05-08 | — | — | EP | disclosed |