Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222951 | 0.82 | CHRNA7 (0.58) | CHRM2CHRM1CHRM3CHRNA7CHRM4 | |
| SCHEMBL3218557 | 0.82 | CHRNA7 (0.58) | CHRM2CHRM1CHRM3CHRNA7CHRM4 | |
| SCHEMBL3206387 | 0.82 | CHRNA7 (0.58) | CHRM2CHRM1CHRM3CHRNA7CHRM4 | |
| Hydrochloric Acid SCHEMBL8988206 | 0.76 | CHRNA7 (0.52) | CHRM2CHRM1CHRM3CHRNA7CHRM4 | |
| SCHEMBL6251745 | 0.75 | CHRNA7 (0.51) | CHRM2CHRM1CHRM3CHRNA7CHRM4 | |
| SCHEMBL3218353 | 0.75 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CHRNA7 | |
| SCHEMBL3218365 | 0.75 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CHRNA7 | |
| SCHEMBL4197310 | 0.74 | CHRNA7 (0.53) | CHRM2CHRM1CHRM3CHRNA7 | |
| SCHEMBL3210424 | 0.74 | GLA (0.54) | CHRM2CHRM1CHRM3CHRNA7CHRM4 | |
| SCHEMBL3210416 | 0.74 | GLA (0.54) | CHRM2CHRM1CHRM3CHRNA7CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212301-A1 | ARYLALKYLOXYALKYLAMINES AND ARYLALKYLTHIOALKYLAMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS INHIBITORS OF NICOTINIC CHOLINERGIC RECEPTORS | Targacept, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-1212301-A1 | ARYLALKYLOXYALKYLAMINES AND ARYLALKYLTHIOALKYLAMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS INHIBITORS OF NICOTINIC CHOLINERGIC RECEPTORS | Targacept, Inc. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001016107-A1 | ARYLALKYLOXYALKYLAMINES AND ARYLALKYLTHIOALKYLAMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS INHIBITORS OF NICOTINIC CHOLINERGIC RECEPTORS | TARGACEPT, INC. (US) | 2001-03-08 | — | — | WO | disclosed |
| WO-2001016107-A1 | ARYLALKYLOXYALKYLAMINES AND ARYLALKYLTHIOALKYLAMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS INHIBITORS OF NICOTINIC CHOLINERGIC RECEPTORS | TARGACEPT, INC. (US) | 2001-03-08 | — | — | WO | disclosed |