Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.48 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335208 | 0.86 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL9335573 | 0.84 | SMN1; SMN2 (0.60) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7545039 | 0.81 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7541252 | 0.80 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL9339099 | 0.80 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL6636319 | 0.79 | CYP3A4 (0.52) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7551726 | 0.78 | MAPT (0.60) | NPC1RAB9ASMN1; SMN2KMT2AMAPT | |
| SCHEMBL7548790 | 0.78 | ALOX5 (0.59) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL9754811 | 0.78 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL7546622 | 0.78 | ALOX5 (0.58) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |