SCHEMBL7544523

SCHEMBL7544523

CCOC(=O)CCc1ccc(C2CCNCC2OCc2ccc3ccccc3c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 19/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041310 0.88 REN (0.73) REN
Bicarbonate SCHEMBL7550821 0.87 REN (0.69) REN
SCHEMBL7553300 0.86 REN (0.65) REN
SCHEMBL6041636 0.85 REN (0.80) REN
Bicarbonate SCHEMBL7554201 0.84 REN (0.73) REN
SCHEMBL7080887 0.83 REN (0.77) REN
SCHEMBL27535945 0.83 REN (0.69) REN
SCHEMBL6960362 0.83 REN (0.80) REN
Hydrochloric Acid SCHEMBL6041395 0.83 REN (0.75) REN
SCHEMBL8204726 0.82 REN (0.78) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1998-09-16 EP disclosed
WO-1997009311-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1997-03-13 WO disclosed