Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431148 | 0.91 | ADORA2A (0.51) | ADORA2A | |
| SCHEMBL7708567 | 0.89 | ADORA2A (0.51) | ADORA2A | |
| SCHEMBL7709135 | 0.86 | ADORA2A (0.58) | ADORA2AF2POLBHPGDKMT2A | |
| SCHEMBL7432349 | 0.82 | ADORA2A (0.49) | ADORA2A | |
| SCHEMBL7426882 | 0.82 | ADORA2A (0.52) | ADORA2A | |
| SCHEMBL7486137 | 0.81 | ADORA2A (0.54) | ADORA2A | |
| SCHEMBL7703121 | 0.80 | ADORA2A (0.62) | ADORA2ASMN1; SMN2 | |
| SCHEMBL7709129 | 0.80 | ADORA2A (0.56) | ADORA2A | |
| SCHEMBL6625057 | 0.79 | ADORA2A (0.67) | ADORA2A | |
| SCHEMBL6870639 | 0.77 | ADORA2A (0.59) | ADORA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214322-A2 | AMINO-TRIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-19 | — | — | EP | disclosed |
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |
| WO-2001017999-A2 | AMINO-TRIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2001-03-15 | — | — | WO | disclosed |