Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544601 | 0.89 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL7431148 | 0.89 | ADORA2A (0.51) | ADORA2A | |
| SCHEMBL7427470 | 0.83 | ADORA2A (0.59) | ADORA2ACSNK1A1CSNK1DCSNK1EADORA2B | |
| SCHEMBL7432349 | 0.82 | ADORA2A (0.49) | ADORA2AADORA3ADORA2B | |
| SCHEMBL7426882 | 0.82 | ADORA2A (0.52) | ADORA2A | |
| SCHEMBL7436829 | 0.75 | ADORA2A (0.49) | ADORA2A | |
| SCHEMBL7709135 | 0.75 | ADORA2A (0.58) | ADORA2A | |
| SCHEMBL6624442 | 0.73 | CSNK1A1 (0.55) | ADORA2ACSNK1A1CSNK1DCSNK1EADORA3 | |
| SCHEMBL7709154 | 0.73 | ADORA2A (0.51) | ADORA2ACSNK1A1CSNK1DCSNK1E | |
| SCHEMBL7705914 | 0.73 | ADORA2A (0.53) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355653-B1 | DRUG AND CARRIER FOR ANTIALLERGENS, BRAIN DISORDERS AND NEUROTRANSMITTERS | HOFFMANN-LA ROCHE INC. | 2002-03-12 | — | — | US | disclosed |