Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.58 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515290 | 0.84 | MAPK1 (0.54) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL27421290 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL7192890 | 0.83 | MAPK13 (0.69) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL16174839 | 0.83 | MAPT (0.54) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL6653205 | 0.83 | MAPK13 (0.75) | ALDH1A1TDP1SMN1; SMN2MAPK13MAPK12 | |
| SCHEMBL4589360 | 0.83 | MAPK1 (0.55) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL4589324 | 0.82 | MAPK13 (0.68) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL21463344 | 0.82 | EPAS1 (0.55) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL30615629 | 0.82 | EPAS1 (0.55) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 | |
| SCHEMBL11517802 | 0.82 | MAPK1 (0.54) | ALDH1A1TDP1L3MBTL1SMN1; SMN2MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002040467-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-05-23 | — | — | WO | disclosed |