Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346619 | 0.86 | ITGB3 (0.41) | ITGB3ITGA2BPOLBMAPTHPGD | |
| SCHEMBL9440466 | 0.83 | ITGB3 (0.41) | ITGB3ITGA2BPOLBMAPTHPGD | |
| SCHEMBL7353190 | 0.82 | POLB (0.42) | ITGB3ITGA2BPOLBMAPTHPGD | |
| SCHEMBL8897705 | 0.81 | ITGB3 (0.43) | ITGB3ITGA2BPOLBMAPTHPGD | |
| SCHEMBL7544610 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL7862736 | 0.81 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL5165511 | 0.79 | ITGB3 (0.65) | ITGB3ITGA2BPOLBMAPTHPGD | |
| SCHEMBL7352610 | 0.79 | ITGB3 (0.65) | ITGB3ITGA2BPOLBMAPTHPGD | |
| SCHEMBL7423126 | 0.79 | POLB (0.45) | ITGB3ITGA2BPOLBMAPTHPGD | |
| SCHEMBL7344666 | 0.78 | ITGB3 (0.47) | ITGB3ITGA2BPOLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997035579-A1 | A METHOD FOR INHIBITING CLOT FORMATION | MERCK & CO., INC. (US) | 1997-10-02 | — | — | WO | claimed |