SCHEMBL7544641

SCHEMBL7544641

C[C@H](CCC=O)[C@H]1CC[C@H]2C(=CC=C3CCCC[C@@H]3C)CCC[C@]12C

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 2/20 0.53
CDC25B P30305 1/20 0.53
VDR P11473 7/20 0.51
ADORA3 P0DMS8 1/20 0.51
SLC6A2 P23975 1/20 0.51
AGTR1 P30556 1/20 0.51
HDAC6 Q9UBN7 3/20 0.50
HDAC3 O15379 2/20 0.50
HDAC2 Q92769 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7544638 1.00 CDC25A (0.53) CDC25ACDC25BVDRADORA3SLC6A2
SCHEMBL4879127 0.86 CDC25A (0.67) CDC25ACDC25BVDRADORA3SLC6A2
SCHEMBL13361581 0.83 VDR (0.74) VDRADORA3SLC6A2AGTR1
SCHEMBL13532023 0.78 VDR (0.76) VDRHDAC6HDAC3HDAC2
SCHEMBL16882253 0.76 CDC25A (0.53) CDC25ACDC25BVDRHDAC6HDAC3
SCHEMBL8971029 0.75 CDC25A (0.54) CDC25ACDC25BVDRHDAC6HDAC3
SCHEMBL7888317 0.75 CDC25A (0.55) CDC25ACDC25BVDRHDAC6HDAC3
SCHEMBL7880445 0.75 CDC25A (0.52) CDC25ACDC25BVDRHDAC6HDAC3
SCHEMBL7888321 0.75 CDC25A (0.55) CDC25ACDC25BVDRHDAC6HDAC3
SCHEMBL12361323 0.75 CDC25A (0.52) CDC25ACDC25BVDRHDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210327-A2 NEW VITAMIN D DERIVATIVES WITH CYCLIC SUBSTRUCTURES IN THE SIDE CHAINS, METHOD AND INTERMEDIATES FOR THEIR PRODUCTION AND THEIR USE IN THE PREPARATION OF MEDICAMENTS Schering Aktiengesellschaft (DE) 2002-06-05 EP claimed
WO-2001007405-A2 NEW VITAMIN D DERIVATIVES WITH CYCLIC SUBSTRUCTURES IN THE SIDE CHAINS, METHOD AND INTERMEDIATES FOR THEIR PRODUCTION AND THEIR USE IN THE PREPARATION OF MEDICAMENTS SCHERING AKTIENGSELLSCHAFT (DE) 2001-02-01 WO claimed
EP-1210327-A2 NEW VITAMIN D DERIVATIVES WITH CYCLIC SUBSTRUCTURES IN THE SIDE CHAINS, METHOD AND INTERMEDIATES FOR THEIR PRODUCTION AND THEIR USE IN THE PREPARATION OF MEDICAMENTS Schering Aktiengesellschaft (DE) 2002-06-05 EP disclosed
WO-2001007405-A2 NEW VITAMIN D DERIVATIVES WITH CYCLIC SUBSTRUCTURES IN THE SIDE CHAINS, METHOD AND INTERMEDIATES FOR THEIR PRODUCTION AND THEIR USE IN THE PREPARATION OF MEDICAMENTS SCHERING AKTIENGSELLSCHAFT (DE) 2001-02-01 WO disclosed