SCHEMBL7544688

SCHEMBL7544688

[CH2]Cn1c(CCCC)nc2c(N)nc3ccccc3c21

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.77
TLR8 Q9NR97 3/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728266 0.90 TLR7 (0.80) TLR7TLR8
SCHEMBL10147925 0.89 TLR7 (0.84) TLR7TLR8
SCHEMBL20623370 0.88 TLR7 (0.89) TLR7TLR8
SCHEMBL3817941 0.87 TLR7 (0.87) TLR7TLR8
SCHEMBL30267787 0.87 TLR7 (1.00) TLR7TLR8
SCHEMBL16487370 0.87 TLR7 (1.00) TLR7TLR8
SCHEMBL25332759 0.86 TLR7 (0.80) TLR7TLR8
SCHEMBL21741933 0.86 TLR7 (0.83) TLR7TLR8
SCHEMBL5350451 0.86 TLR7 (0.79) TLR7TLR8
SCHEMBL6246349 0.86 TLR7 (0.73) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1187613-A4 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2002-07-24 EP claimed
EP-1187613-A1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-03-20 EP claimed
WO-2000076505-A1 AMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO claimed