SCHEMBL7544746

SCHEMBL7544746

CCCCc1c(O)ccc(O)c1O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.52
NPC1 O15118 1/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
RAB9A P51151 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
TYR P14679 2/20 0.48
ALOX5 P09917 5/20 0.44
KDM4E B2RXH2 2/20 0.43
PKM P14618 1/20 0.43
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41
IAPP P10997 1/20 0.40
AR P10275 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280911 0.93 TYR (0.56) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL710654 0.88 HPGD (0.58) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL30026986 0.88 HPGD (0.58) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL9155666 0.87 HPGD (0.48) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL4955648 0.87 HPGD (0.48) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL10355484 0.85 TYR (0.62) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL887689 0.85 TYR (0.58) HPGDNPC1MAPK1HTTRAB9A
Methoxymethane SCHEMBL712957 0.84 HPGD (0.54) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL27621118 0.84 TYR (0.55) HPGDNPC1MAPK1HTTRAB9A
SCHEMBL5921665 0.84 HPGD (0.46) HPGDNPC1MAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1121489-C Method of manufacturing detergent composition UNILEVER NV (NL) 2003-09-17 CN disclosed
EP-0709086-B1 Discrete particles and method of making same BIOVAIL TECH LTD (US) 2002-05-15 EP disclosed
US-6083430-A HEATING, CENTRIFUGING, SHEARING FUISZ TECHNOLOGIES LTD. (US) 2000-07-04 US disclosed
US-5965164-A FOR ORAL USE, COMPRISING SHEARLITE PARTICLES (MADE UNDER LIQUIFLASH CONDITIONS) OF BIO-AFFECTING AGENT IN METERED DOSE WHICH ARE FLOWABLE TO BE ADMINISTERED UNDER GRAVITY, AND A BIFUNCTIONAL VESSEL FOR STORAGE AND TRANSPORTATION FUISZ TECHNOLOGIES LTD. (US) 1999-10-12 US disclosed
US-5849223-A Liquiflash particles and method of making same FUISZ TECHNOLOGIES LTD. (US) 1998-12-15 US disclosed
CN-1169468-A Method of manufacturing detergent composition UNILEVER NV (NL) 1998-01-07 CN disclosed
WO-1997040820-A1 RECIPIENT-DOSAGE DELIVERY SYSTEM FUISZ TECHNOLOGIES LTD. (US) 1997-11-06 WO disclosed
US-5683720-A Liquiflash particles and method of making same FUISZ TECHNOLOGIES LTD. (US) 1997-11-04 US disclosed
EP-0709086-A2 Discrete particles and method of making same FUISZ TECHNOLOGIES LTD. (US) 1996-05-01 EP disclosed