Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30026986 | 0.95 | HPGD (0.58) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL710654 | 0.95 | HPGD (0.58) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL27621118 | 0.91 | TYR (0.55) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL292316 | 0.88 | ALOX5 (0.50) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL72998 | 0.88 | TYR (0.57) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL11098787 | 0.86 | NPC1 (0.50) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL30945822 | 0.86 | HPGD (0.50) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL62285 | 0.86 | HPGD (0.50) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL6271499 | 0.86 | TYR (0.60) | HPGDNPC1MAPK1HTTRAB9A | |
| SCHEMBL10337301 | 0.86 | TYR (0.60) | HPGDNPC1MAPK1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150826-A1 | DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2024-07-18 | — | — | WO | disclosed |
| CN-118338879-A | Curable composition for dental use | 可乐丽则武齿科株式会社 | 2024-07-12 | — | — | CN | disclosed |
| US-12030970-B2 | Curable composition and stereolithographic resin composition comprising same | KURARAY CO., LTD. (JP) | 2024-07-09 | — | — | US | disclosed |
| US-20240164993-A1 | ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME | KURARAY NORITAKE DENTAL INC. (JP) | 2024-05-23 | — | — | US | disclosed |
| CN-114072439-B | Curable composition and resin composition for photofabrication comprising same | 株式会社可乐丽 | 2024-05-14 | — | — | CN | disclosed |
| US-11981763-B2 | Resin composition for stereolithographic modeling | KURARAY NORITAKE DENTAL INC. (JP) | 2024-05-14 | — | — | US | disclosed |
| WO-2024096019-A1 | DENTAL ADHESIVE COMPOSITION | クラレノリタケデンタル株式会社 | 2024-05-10 | — | — | WO | disclosed |
| US-20240139078-A1 | DENTAL FILLING KIT | KURARAY NORITAKE DENTAL INC. (JP) | 2024-05-02 | — | — | US | disclosed |
| EP-4360609-A1 | DENTAL ADHESIVE KIT | Kuraray Noritake Dental Inc. (JP) | 2024-05-01 | — | — | EP | disclosed |
| CN-113993497-B | Curable composition and resin composition for photofabrication comprising same | 株式会社可乐丽 | 2024-03-22 | — | — | CN | disclosed |
| CN-102083403-A | Dental composition and composite resin | KURARAY MEDICAL INC | 2011-06-01 | — | — | CN | disclosed |
| US-7951851-B2 | Curable composition for dental purposes | KURARAY MEDICAL INC. (JP) | 2011-05-31 | — | — | US | disclosed |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | KURARAY MEDICAL INC. (JP) | 2011-02-24 | — | — | US | disclosed |
| EP-2275076-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | Kuraray Medical Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-20110003267-A1 | DENTAL COMPOSITION | KURARAY MEDICAL INC. (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20100105802-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | KURARAY MEDICAL INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| CN-101605524-A | Dental composition | KURARAY MEDICAL INC (JP) | 2009-12-16 | — | — | CN | disclosed |
| CN-101600412-A | Curable composition for dental use | KURARAY MEDICAL INC (JP) | 2009-12-09 | — | — | CN | disclosed |
| EP-2123247-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | Kuraray Medical Inc. (JP) | 2009-11-25 | — | — | EP | disclosed |
| EP-2119425-A1 | DENTAL COMPOSITION | Kuraray Medical Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240139078-A1 | DENTAL FILLING KIT | DHX29, DHX35, DHX15 | HPGD 1417/4885NPC1 4339/4885MAPK1 3162/4885 |
| US-20100105802-A1 | CURABLE COMPOSITION FOR DENTAL PURPOSES | H1-0, H1-3, H1-2 | HPGD 2648/4885NPC1 4783/4885MAPK1 4062/4885 |
| US-12030970-B2 | Curable composition and stereolithographic resin composition comprising same | ARL1, ASH2L, VCL | HPGD 3840/4885NPC1 4837/4885MAPK1 3811/4885 |
| US-20110046261-A1 | DENTAL COMPOSITION AND COMPOSITE RESIN | CAD, KATNAL2, ZYX | HPGD 2452/4885NPC1 3367/4885MAPK1 3931/4885 |
| US-20110003267-A1 | DENTAL COMPOSITION | NLRP3, TAS2R42, CAD | HPGD 219/4885NPC1 4506/4885MAPK1 4470/4885 |
| US-20240164993-A1 | ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME | MSL1, ITGA1, ASH2L | HPGD 1548/4885NPC1 3994/4885MAPK1 3293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.