Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 9/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.45 |
| ▸ | GRN | P28799 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.41 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.41 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.41 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.41 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.41 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.41 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.41 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.41 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572757 | 0.93 | ITGB1 (0.50) | ITGB1ITGA4 | |
| SCHEMBL7541830 | 0.92 | ITGB1 (0.46) | ITGB1ITGA4ALDH1A1LMNAMAPT | |
| SCHEMBL7542066 | 0.92 | ITGB1 (0.47) | ITGB1ITGA4MAPK1MAPT | |
| SCHEMBL7546407 | 0.91 | ANPEP (0.51) | ITGB1ITGA4PSMB11PSMA7PSMB1 | |
| SCHEMBL7539575 | 0.89 | CTSL (0.39) | ITGB1ITGA4GRNSORT1ALDH1A1 | |
| SCHEMBL7538323 | 0.89 | ITGB1 (0.43) | ITGB1ITGA4ALDH1A1LMNAMAPT | |
| SCHEMBL7545934 | 0.89 | GRN (0.37) | ITGB1ITGA4GRNSORT1ALDH1A1 | |
| SCHEMBL7538590 | 0.88 | GRN (0.45) | ITGB1ITGA4GRNSORT1ALDH1A1 | |
| SCHEMBL7545926 | 0.87 | ITGB1 (0.44) | ITGB1ITGA4GRNSORT1ALDH1A1 | |
| SCHEMBL7538889 | 0.87 | ITGB1 (0.44) | ITGB1ITGA4GRNSORT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |