Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10758257 | 0.86 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7545039 | 0.83 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL16044245 | 0.82 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| 2-(Phenoxymethyl)Benzothiazole SCHEMBL2245843 | 0.81 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL30354907 | 0.81 | EPHX2 (0.59) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7543995 | 0.81 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL29151274 | 0.81 | EPHX2 (0.59) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL30354837 | 0.80 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL29151295 | 0.80 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7541252 | 0.79 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955968-A | Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof | 韩国科学技术研究院 | 2023-04-11 | — | — | CN | disclosed |
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| CN-1073097-C | Aniline derivatives having herbicidal activity their prepn. and their use | SANKYO CO (JP) | 2001-10-17 | — | — | CN | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| CN-1176962-A | Aniline derivatives having herbicidal activity their prepn. and their use | SANKYO CO (JP) | 1998-03-25 | — | — | CN | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |