Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7543706 | 0.92 | DYRK1A (0.56) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL7551595 | 0.90 | ALOX5 (0.51) | NPC1RAB9ASMN1; SMN2DYRK1AMAPT | |
| SCHEMBL7548792 | 0.89 | DYRK1A (0.51) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL7543795 | 0.89 | ALOX5 (0.61) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL7541718 | 0.88 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL7542457 | 0.88 | ALOX5 (0.62) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL7541047 | 0.86 | ALOX5 (0.46) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL7542768 | 0.84 | MAPT (0.64) | NPC1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL7542633 | 0.84 | ALOX5 (0.50) | NPC1RAB9ASMN1; SMN2HTTDYRK1A | |
| SCHEMBL7542041 | 0.83 | DYRK1A (0.51) | NPC1RAB9ASMN1; SMN2DYRK1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795550-B1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0795550-A1 | Aniline derivatives having herbicidal activity their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |