Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6740163 | 0.85 | CTSS (0.42) | CTSSCTSLCTSB | |
| SCHEMBL6063311 | 0.81 | CTSS (0.49) | CTSSCTSLCTSB | |
| SCHEMBL6063309 | 0.81 | CTSS (0.49) | CTSSCTSLCTSB | |
| SCHEMBL6739784 | 0.80 | CTSS (0.46) | CTSSCTSLCTSB | |
| SCHEMBL1557679 | 0.80 | CTSS (0.50) | CTSSCTSLCTSB | |
| SCHEMBL1987948 | 0.80 | CTSS (0.50) | CTSSCTSLCTSB | |
| SCHEMBL1557652 | 0.79 | CTSS (0.52) | CTSSCTSLCTSB | |
| SCHEMBL1557648 | 0.79 | CTSS (0.52) | CTSSCTSLCTSB | |
| SCHEMBL5436195 | 0.79 | CTSS (0.46) | CTSSCTSLCTSB | |
| SCHEMBL6743322 | 0.79 | CTSS (0.46) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212302-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001019796-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |