Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760618 | 0.79 | PNMT (0.49) | PNMTNPC1RAB9AKDRHTR7 | |
| SCHEMBL7536527 | 0.76 | PNMT (0.46) | PNMTNPC1RAB9AKDRCASP6 | |
| SCHEMBL524602 | 0.70 | PNMT (0.63) | PNMTNPC1RAB9AKDRCASP6 | |
| SCHEMBL30103334 | 0.70 | PNMT (0.63) | PNMTNPC1RAB9AKDRCASP6 | |
| SCHEMBL68635 | 0.69 | NPC1 (0.55) | PNMTNPC1RAB9APDGFRBKDR | |
| SCHEMBL2877998 | 0.68 | PNMT (0.61) | PNMTNPC1RAB9AKDRCASP6 | |
| SCHEMBL6628576 | 0.67 | CYP2C9 (0.56) | NPC1RAB9AHTR7HTR2BHSP90AA1 | |
| SCHEMBL22263591 | 0.66 | PNMT (0.57) | PNMTNPC1RAB9AKDRCASP6 | |
| SCHEMBL70992 | 0.65 | PNMT (0.53) | PNMTNPC1RAB9AKDRHTR7 | |
| SCHEMBL29401802 | 0.65 | PNMT (0.53) | PNMTNPC1RAB9AKDRHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841375-B1 | Impact-resistant polystyrene resin composition | UBE INDUSTRIES (JP) | 2002-05-22 | — | — | EP | disclosed |
| US-5981667-A | CONTAINING DISPERSED PARTICLES OF HIGH-CIS HIGH-VINYL POLYBUTADIENE COMPRISING FROM 65 TO 95% CIS-1,4-STRUCTURES AND FROM 30 TO 4% 1,2-STRUCTURES | UBE INDUSTRIES, LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0841375-A1 | Impact-resistant polystyrene resin composition | UBE INDUSTRIES, LTD. (JP) | 1998-05-13 | — | — | EP | disclosed |