Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | GPR174 | Q9BXC1 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546017 | 0.85 | MAPT (0.71) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL7544057 | 0.85 | MAPT (0.69) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL3537291 | 0.83 | ALDH1A1 (0.74) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL8069195 | 0.82 | MAPT (0.69) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL8069380 | 0.82 | MAPT (0.69) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL3535719 | 0.81 | ALDH1A1 (0.77) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL8071105 | 0.80 | MAPT (0.68) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL22578965 | 0.79 | MAPT (0.65) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL5235247 | 0.78 | MAPK1 (0.64) | MAPK1MAPTPKMALDH1A1LMNA | |
| SCHEMBL5236640 | 0.78 | MAPK1 (0.64) | MAPK1MAPTPKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970040-B1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 2002-06-12 | — | — | EP | claimed |
| EP-0970040-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | Clariant GmbH (DE) | 2000-01-12 | — | — | EP | claimed |
| WO-1998040348-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 1998-09-17 | — | — | WO | claimed |
| EP-0970040-B1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-0970040-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | Clariant GmbH (DE) | 2000-01-12 | — | — | EP | disclosed |
| US-5990309-A | 2-chloro-5-fluoro-4-morpholinonitrobenzene and 2-chloro-5-fluoro-4-morpholinoaniline | CLARIANT GMBH (DE) | 1999-11-23 | — | — | US | disclosed |
| US-5917037-A | Process for the preparation of n-carboxyalkyl-3-fluoro-4-dialkylaminoanilines | CLARIANT GMBH (DE) | 1999-06-29 | — | — | US | disclosed |
| WO-1998040348-A1 | METHOD FOR PRODUCING N-CARBOXYALKYL-3-FLUORO-4-DIALKYLAMINONILINES | CLARIANT GMBH (DE) | 1998-09-17 | — | — | WO | disclosed |