SCHEMBL7545299

SCHEMBL7545299

C=CCc1cccc(OCO)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.44
CYP4A11 Q02928 1/20 0.44
XDH P47989 1/20 0.43
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 3/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
MEN1 O00255 2/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
ALDH2 P05091 1/20 0.42
GABRA1 P14867 1/20 0.42
AKR1B1 P15121 1/20 0.42
HPGD P15428 1/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
GABRB2 P47870 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP3A4 P08684 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11127858 0.85 ALDH1A1 (0.42) CYP4F2CYP4A11XDHALDH1A1KDM4E
SCHEMBL2093704 0.84 ALDH1A1 (0.41) CYP4F2CYP4A11XDHALDH1A1KDM4E
SCHEMBL2318952 0.84 KDM4E (0.50) XDHALDH1A1KDM4EPPARGPPARD
SCHEMBL8406148 0.81 ALDH1A1 (0.44) XDHALDH1A1KDM4EPPARGPPARD
SCHEMBL9434797 0.81 BCHE (0.58) CYP4F2CYP4A11ALDH1A1KDM4EMEN1
SCHEMBL3380222 0.80 ALDH1A1 (0.43) CYP4F2CYP4A11XDHALDH1A1KDM4E
SCHEMBL5830773 0.80 PPARA (0.56) KDM4EPPARGNPC1RAB9APPARA
SCHEMBL2091144 0.79 ALDH1A1 (0.43) XDHALDH1A1KDM4EPPARGPPARD
SCHEMBL12042852 0.79 ALDH1A1 (0.45) ALDH1A1KDM4EPPARGPPARDMEN1
SCHEMBL29382328 0.78 ALDH1A1 (0.60) ALDH1A1PPARGPPARDCYP3A4ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002045731-A1 ACTIVITY OF EXTRACT OF PIPER BETLE LEAVES AGAINST LEISHMANIA COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-06-13 WO disclosed
US-6284868-B1 AT LEAST ONE 1-ALKENE THAT IS AN ARYL DERIVATIVE SUBSTITUTED WITH AT LEAST ONE TERMINAL ALLYL AND/OR HOMOALLYL MOIETY AND CONTAINING ONE OR MORE POLAR GROUPS; GROUP VIII METAL COMPLEX CATALYST BASF AKTIENGESELLSCHAFT (DE) 2001-09-04 US disclosed
EP-0991696-A1 FUNCTIONALISED CARBON MONOXIDE COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 2000-04-12 EP disclosed
WO-1999000443-A1 FUNCTIONALISED CARBON MONOXIDE COPOLYMERS BASF AKTIENGESELLSCHAFT (DE) 1999-01-07 WO disclosed