SCHEMBL7545405

SCHEMBL7545405

N#CC(Cl)(c1ccc(Cl)cc1)c1ccc(-n2ncc(=O)[nH]c2=O)cc1Cl

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.55
NR1I2 O75469 1/20 0.55
KMT2A Q03164 1/20 0.55
P2RX7 Q99572 11/20 0.39
ABCB11 O95342 1/20 0.38
THRB P10828 8/20 0.36
THRA P10827 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10395321 0.94 KMT2A (0.50) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL10420132 0.91 MEN1 (0.49) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL10421420 0.89 KMT2A (0.57) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL8603426 0.88 KMT2A (0.54) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL6479147 0.86 MEN1 (0.54) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL10667155 0.84 MEN1 (0.50) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL9787370 0.82 DDB1 (0.38) MEN1NR1I2KMT2A
SCHEMBL10670462 0.82 MEN1 (0.50) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL10420835 0.81 MEN1 (0.49) MEN1NR1I2KMT2AP2RX7ABCB11
SCHEMBL5566669 0.80 MEN1 (0.49) MEN1NR1I2KMT2AP2RX7ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377904-B1 AGENT AGAINST PROTOZOAE IN INSECTS BAYER AG (DE) 1993-08-18 EP claimed
EP-0353526-B1 AGENT AGAINST FISH PARASITES CONTAINING TRIAZINEDIONE DERIVATIVES BAYER AG (DE) 1993-05-26 EP claimed
US-5070091-A HONEY BEES BAYER AKTIENGESELLSCHAFT (DE) 1991-12-03 US claimed
CN-111574411-A Preparation method of diclazuril impurity B 常州齐晖药业有限公司 2020-08-25 CN disclosed
CN-111517991-A Preparation method of diclazuril impurity A 常州齐晖药业有限公司 2020-08-11 CN disclosed
EP-0879057-B1 GRANULES FROM TRIAZINES BAYER AG (DE) 2002-06-05 EP disclosed
US-6004585-A DUST FREE, EASILY FLOWABLE AND DOSABLE GRANULAR COMPOSITIONS CONTAINING TRIAZINE COMPOUND; CAN BE MIXED WITH FEED FOR ADMINISTRATION TO ANIMALS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed
US-5464837-A Antiprotozoa agents and insecticides BAYER AKTIENGESELLSCHAFT (DE) 1995-11-07 US disclosed
EP-0377904-B1 AGENT AGAINST PROTOZOAE IN INSECTS BAYER AG (DE) 1993-08-18 EP disclosed
EP-0353526-B1 AGENT AGAINST FISH PARASITES CONTAINING TRIAZINEDIONE DERIVATIVES BAYER AG (DE) 1993-05-26 EP disclosed
US-5070091-A HONEY BEES BAYER AKTIENGESELLSCHAFT (DE) 1991-12-03 US disclosed
EP-0377904-A2 Agent against protozoae in insects BAYER AG (DE) 1990-07-18 EP disclosed
EP-0353526-A2 Agent against fish parasites containing triazinedione derivatives BAYER AG (DE) 1990-02-07 EP disclosed