Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 10/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545866 | 1.00 | ADRB2 (0.56) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7548498 | 0.98 | ADRB2 (0.56) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7549100 | 0.89 | ADRB2 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7549102 | 0.89 | ADRB2 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7543045 | 0.88 | ADRB2 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7543034 | 0.88 | ADRB2 (0.54) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7546363 | 0.85 | ADRB3 (0.57) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7550482 | 0.83 | ADRB3 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7550490 | 0.83 | ADRB3 (0.47) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7542010 | 0.83 | ADRB2 (0.56) | ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894787-B1 | 3,4-DISUBSTITUTED PHENYLETHANOLAMINOTETRALINCARBOXYLATE DERIVATIVES | KISSEI PHARMACEUTICAL (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6136852-A | 3,4-disubstituted phenylethanolaminotetralincarboxylic acid derivatives | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0894787-A1 | 3,4-DISUBSTITUTED PHENYLETHANOLAMINOTETRALINCARBOXYLATE DERIVATIVES | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1999-02-03 | — | — | EP | disclosed |