Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 19/20 | 0.66 |
| ▸ | ITGA4 | P13612 | 18/20 | 0.66 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.66 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.64 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222489 | 0.91 | ITGA4 (0.74) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1222491 | 0.91 | ITGA4 (0.74) | ITGB1ITGA4ITGB7 | |
| SCHEMBL13726200 | 0.89 | ITGB1 (0.70) | ITGB1ITGA4ITGB7ITGA2ITGA5 | |
| SCHEMBL5783011 | 0.89 | ITGA4 (0.65) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5787132 | 0.89 | ITGA4 (0.65) | ITGB1ITGA4ITGB7 | |
| SCHEMBL7538961 | 0.88 | ITGB1 (0.73) | ITGB1ITGA4ITGB7ITGA2ITGA5 | |
| SCHEMBL5784933 | 0.87 | ITGA4 (0.68) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5785174 | 0.87 | ITGA4 (0.70) | ITGB1ITGA4ITGB7 | |
| SCHEMBL5787343 | 0.86 | ITGB1 (0.59) | ITGB1ITGA4ITGB7ITGA2 | |
| SCHEMBL6473724 | 0.86 | ITGB1 (0.59) | ITGB1ITGA4ITGB7ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1209147-A1 | CARBOXYLIC ACID DERIVATIVES AND ADHESION MOLECULE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2002-05-29 | — | — | EP | disclosed |