Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.39 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 4/20 | 0.37 |
| ▸ | TOP2A | P11388 | 12/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504904 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7502899 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7498238 | 0.95 | KCNH2 (0.35) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7497788 | 0.95 | KCNH2 (0.35) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7507361 | 0.94 | KCNH2 (0.35) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7506511 | 0.93 | KCNH2 (0.34) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7503826 | 0.90 | KCNH2 (0.37) | ALDH1A1KCNH2SCN5A | |
| SCHEMBL7506270 | 0.88 | KCNH2 (0.44) | KCNH2TOP1 | |
| SCHEMBL7502770 | 0.88 | KCNH2 (0.37) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL7502765 | 0.88 | TOP1 (0.39) | ALDH1A1POLBCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723545-B1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LAB (US) | 2002-05-08 | — | — | EP | claimed |