SCHEMBL754642

SCHEMBL754642

Brc1ccc(Oc2ccccc2)c(Br)c1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.46
TSHR P16473 1/20 0.46
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NTRK1 P04629 1/20 0.40
NTRK3 Q16288 1/20 0.40
NTRK2 Q16620 1/20 0.40
LMNA P02545 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
TTR P02766 2/20 0.39
TDP1 Q9NUW8 1/20 0.38
HRH1 P35367 1/20 0.37
CTNNB1 P35222 1/20 0.37
NR1H2 P55055 1/20 0.37
BAX Q07812 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL573706 0.83 TSHR (0.46) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL22361231 0.83 MAPT (0.45) TSHRSLC6A4TDP1MAOA
SCHEMBL29494593 0.83 TSHR (0.46) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL28485565 0.82 TDP1 (0.46) TSHRLMNAKMT2ATDP1
SCHEMBL4190024 0.81 TDP1 (0.55) TSHRLMNAKMT2ATDP1
SCHEMBL29492146 0.81 TDP1 (0.55) TSHRLMNAKMT2ATDP1
SCHEMBL755527 0.81 TDP1 (0.64) LTA4HTSHRCYP1A2CYP3A4CYP2C9
SCHEMBL30076271 0.80 EGFR (0.42) CYP1A2CYP3A4CYP2C9CYP2C19LMNA
SCHEMBL9780467 0.79 LTA4H (0.52) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL10766306 0.79 MAPT (0.52) TSHRCYP3A4GAAKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114611954-A Ecological risk evaluation method and system for mangrove forest ecosystem 生态环境部华南环境科学研究所 2022-06-10 CN claimed
WO-2004076543-A1 FIRE RETARDANT FILM BRITISH POLYTHENE LIMITED (GB) 2004-09-10 WO claimed
US-5357027-A Fireproof, heat resistant, impact resistant molding materials IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-10-18 US claimed
US-4327197-A Fire-retardant anhydride copolymers ATLANTIC RICHFIELD COMPANY (US) 1982-04-27 US claimed
US-4326044-A Fire-retardant monocarboxylic acid copolymers ATLANTIC RICHFIELD COMPANY (US) 1982-04-20 US claimed
US-4323655-A Rubber-modified fire-retardant anhydride copolymers ATLANTIC RICHFIELD COMPANY (US) 1982-04-06 US claimed
US-4312958-A Fire-retardant, rubber-modified, monocarboxylic acid copolymers ATLANTIC RICHFIELD COMPANY (US) 1982-01-26 US claimed
US-4304874-A Fire-retardant anhydride copolymers ARCO POLYMERS, INC. (US) 1981-12-08 US claimed
US-4298705-A Rubber-modified fire-retardant imide copolymers ARCO POLYMERS, INC. (US) 1981-11-03 US claimed
US-4298704-A Fire-retardant monocarboxylic acid amide copolymers ARCO POLYMERS, INC. (US) 1981-11-03 US claimed
US-4298703-A Fire-retardant imide copolymers ARCO POLYMERS, INC. (US) 1981-11-03 US claimed
US-4286070-A Fire-retardant, rubber-modified, monocarboxylic acid copolymers ARCO POLYMERS, INC. (US) 1981-08-25 US claimed
US-4278768-A Rubber-modified fire-retardant anhydride copolymers ARCO POLYMERS, INC. (US) 1981-07-14 US claimed
US-4278767-A Fire-retardant monocarboxylic acid copolymers ARCO POLYMERS, INC. (US) 1981-07-14 US claimed
US-4271271-A Fire-retardant monocarboxlylic acid amide copolymers ARCO POLYMERS, INC. (US) 1981-06-02 US claimed
US-4266037-A Fire-retardant imide copolymers ARCO POLYMERS, INC. (US) 1981-05-05 US claimed
US-4266038-A Rubber-modified fire-retardant imide copolymers ARCO POLYMERS, INC. (US) 1981-05-05 US claimed
US-4056656-A PHENOLIC RESIN, PENTABROMODIPHENYL ETHER, PLASTICIZER DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1977-11-01 US claimed
CN-119899594-A Adhesive tape for electronic product and preparation method thereof 飞比达电子元器件(苏州)有限公司 2025-04-29 CN disclosed
US-4010219-A HALOGENATED DIPHENYL ETHER TORAY INDUSTRIES, INC. (JA) 1977-03-01 US disclosed