Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.53 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437432 | 0.98 | GSR (0.55) | GSRGNAI3GNAO1GNAI1PAOX | |
| SCHEMBL28989917 | 0.85 | GRIK1 (0.47) | GNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL28989949 | 0.85 | GRIK1 (0.47) | GNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL28989906 | 0.85 | GRIK1 (0.47) | GNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL28989897 | 0.85 | GRIK1 (0.47) | GNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL27791383 | 0.84 | DPP7 (0.39) | GSRDPP7DPP8DPP9DPP4 | |
| SCHEMBL7547287 | 0.83 | GSR (0.38) | GSRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL1356592 | 0.82 | GSR (0.59) | GSRGNAI3GNAO1GNAI1PAOX | |
| SCHEMBL5682768 | 0.82 | GSR (0.59) | GSRGNAI3GNAO1GNAI1PAOX | |
| SCHEMBL27429278 | 0.82 | GSR (0.59) | GSRGNAI3GNAO1GNAI1PAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941123-B1 | NUCLEIC ACID COMPLEXED WITH CATIONIC POLYMER USEFUL FOR GENE THERAPY | HYBRID SYSTEMS LTD (GB) | 2002-06-12 | — | — | EP | claimed |
| US-6312727-B1 | SYNTHETIC POLYMER CARRIER VEHICLE FOR DELIVERY OF NUCLEIC ACID TO TARGET CELLS IN BIOLOGICAL SYSTEMS | HYBRID SYSTEMS LIMITED (GB) | 2001-11-06 | — | — | US | claimed |
| EP-0941123-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT, Etienne Honoré (BE) | 1999-09-15 | — | — | EP | claimed |
| WO-1998019710-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT ETIENNE HONORE (BE) | 1998-05-14 | — | — | WO | claimed |
| EP-0941123-B1 | NUCLEIC ACID COMPLEXED WITH CATIONIC POLYMER USEFUL FOR GENE THERAPY | HYBRID SYSTEMS LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| US-6312727-B1 | SYNTHETIC POLYMER CARRIER VEHICLE FOR DELIVERY OF NUCLEIC ACID TO TARGET CELLS IN BIOLOGICAL SYSTEMS | HYBRID SYSTEMS LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |
| EP-0941123-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT, Etienne Honoré (BE) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998019710-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT ETIENNE HONORE (BE) | 1998-05-14 | — | — | WO | disclosed |