Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 5/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.35 |
| ▸ | NOS3 | P29474 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 3/20 | 0.32 |
| ▸ | ARG2 | P78540 | 3/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437432 | 0.85 | GSR (0.55) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL7546678 | 0.83 | GSR (0.53) | GSRNOS2GNAI3GNAO1GNAI1 | |
| SCHEMBL28989917 | 0.79 | GRIK1 (0.47) | TSHRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL28989906 | 0.79 | GRIK1 (0.47) | TSHRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL28989897 | 0.79 | GRIK1 (0.47) | TSHRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL28989949 | 0.79 | GRIK1 (0.47) | TSHRGNAI3GNAO1GNAI1DPP7 | |
| SCHEMBL27791383 | 0.78 | DPP7 (0.39) | GSRTSHRDPP7DPP4DPP8 | |
| SCHEMBL7024850 | 0.78 | ALDH1A1 (0.49) | GSRCYP1A2TSHR | |
| SCHEMBL5961633 | 0.77 | NOS2 (0.50) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL18499975 | 0.76 | GSR (0.64) | GSRGNAI3GNAO1GNAI1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941123-B1 | NUCLEIC ACID COMPLEXED WITH CATIONIC POLYMER USEFUL FOR GENE THERAPY | HYBRID SYSTEMS LTD (GB) | 2002-06-12 | — | — | EP | claimed |
| US-6312727-B1 | SYNTHETIC POLYMER CARRIER VEHICLE FOR DELIVERY OF NUCLEIC ACID TO TARGET CELLS IN BIOLOGICAL SYSTEMS | HYBRID SYSTEMS LIMITED (GB) | 2001-11-06 | — | — | US | claimed |
| EP-0941123-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT, Etienne Honoré (BE) | 1999-09-15 | — | — | EP | claimed |
| WO-1998019710-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT ETIENNE HONORE (BE) | 1998-05-14 | — | — | WO | claimed |
| EP-0941123-B1 | NUCLEIC ACID COMPLEXED WITH CATIONIC POLYMER USEFUL FOR GENE THERAPY | HYBRID SYSTEMS LTD (GB) | 2002-06-12 | — | — | EP | disclosed |
| US-6312727-B1 | SYNTHETIC POLYMER CARRIER VEHICLE FOR DELIVERY OF NUCLEIC ACID TO TARGET CELLS IN BIOLOGICAL SYSTEMS | HYBRID SYSTEMS LIMITED (GB) | 2001-11-06 | — | — | US | disclosed |
| EP-0941123-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT, Etienne Honoré (BE) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998019710-A2 | DELIVERY OF NUCLEIC ACID MATERIAL TO TARGET CELLS IN BIOLOGICAL SYSTEMS | SCHACHT ETIENNE HONORE (BE) | 1998-05-14 | — | — | WO | disclosed |