SCHEMBL7546776

SCHEMBL7546776

CN1CCN=C1c1cccc(Oc2nc(Oc3cc(C(N)=O)ccc3O)c(F)c(N3CCC(C(=O)O)CC3)c2F)c1

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 14/20 0.65
F2 P00734 12/20 0.65
PLG P00747 4/20 0.42
PLAU P00749 4/20 0.42
PLAT P00750 4/20 0.42
NEK2 P51955 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6576178 0.94 F10 (0.74) F10F2PLGPLAUPLAT
SCHEMBL6576934 0.86 F10 (0.70) F10F2PLGPLAUPLAT
SCHEMBL6579641 0.86 F10 (0.74) F10F2
SCHEMBL6581356 0.83 F10 (0.74) F10F2
SCHEMBL6576738 0.83 F10 (0.74) F10F2
SCHEMBL6578632 0.82 F10 (0.78) F10F2PLGPLAUPLAT
SCHEMBL6578558 0.82 F10 (0.75) F10F2PLGPLAUPLAT
SCHEMBL6579903 0.82 F10 (0.72) F10F2PLGPLAUPLAT
SCHEMBL6581540 0.81 F10 (0.72) F10F2PLGPLAUPLAT
SCHEMBL7550943 0.81 F10 (0.63) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032223-A1 Benzamidine derivatives and their use as anti-coagulants BERLEX LABORATORIES, INC. 2002-03-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020032223-A1 Benzamidine derivatives and their use as anti-coagulants SERPINC1, HABP2, SERPINE1 F10 44/4885F2 4/4885PLG 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.