SCHEMBL7546905

SCHEMBL7546905

c1ccc(COCCCOc2ccc(C3C(OCCOC4CCCCO4)CNCC3OCc3ccc4cccnc4c3)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7447070 0.99 REN (0.66) REN
SCHEMBL7543276 0.90 REN (0.71) REN
SCHEMBL6949364 0.90 REN (0.80) REN
SCHEMBL6949370 0.90 REN (0.80) REN
Hydrochloric Acid SCHEMBL6041568 0.89 REN (0.79) REN
Hydrochloric Acid SCHEMBL6041563 0.89 REN (0.79) REN
SCHEMBL6042155 0.88 REN (0.55) REN
SCHEMBL6042147 0.88 REN (0.55) REN
SCHEMBL7085106 0.88 REN (0.54) REN
SCHEMBL6043076 0.87 REN (0.55) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1998-09-16 EP disclosed
WO-1997009311-A1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY F. HOFFMANN-LA ROCHE AG (CH) 1997-03-13 WO disclosed