SCHEMBL7547097

SCHEMBL7547097

CCOC(=O)CCCCCCCCCCCCCCCCCN

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.83
PAOX Q6QHF9 1/20 0.52
DGKA P23743 1/20 0.52
ALDH1A1 P00352 3/20 0.51
ALOX15 P16050 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
TSHR P16473 2/20 0.51
CYP3A4 P08684 1/20 0.51
HSD17B10 Q99714 1/20 0.51
GAA P10253 2/20 0.50
CPB2 Q96IY4 1/20 0.49
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
PLG P00747 1/20 0.48
LMNA P02545 1/20 0.48
THRB P10828 1/20 0.48
SLC6A2 P23975 1/20 0.48
RECQL P46063 1/20 0.48
SLC6A3 Q01959 1/20 0.48
PAM P19021 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4919758 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL1463911 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL1471510 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL4915851 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL4915881 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL4915709 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL4925671 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL3284074 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL2967294 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15
SCHEMBL7543573 1.00 CYP1A2 (0.83) CYP1A2PAOXDGKAALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885886-B1 PYRIDINECARBOXAMIDE DERIVATIVES NISSHIN SEIFUN GROUP INC (JP) 2002-05-29 EP disclosed
US-5972943-A N-(NITRIC ACID,C14-18 ALKYL ESTER)-6-(1-(OPTIONALLY 4-SUBSTITUTED PIPERAZINYL)) PYRIDINE-3-CARBOXAMIDES; METHOD OF SYNTHESIS; ADMINISTERING TO TREAT CEREBRAL EDEMA; NO HYPOTENSIVE SIDE EFFECT NISSHIN FLOUR MILLING CO., LTD. (JP) 1999-10-26 US disclosed
EP-0885886-A1 NOVEL PYRIDINECARBOXAMIDE DERIVATIVES Nisshin Flour Milling Co., Ltd. (JP) 1998-12-23 EP disclosed
US-4165329-A CARBOXYLATED UREA METAL SALTS CHEVRON RESEARCH COMPANY (US) 1979-08-21 US disclosed