Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.83 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919758 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL1463911 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL1471510 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL4915851 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL4915881 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL4915709 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL4925671 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL2967294 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL7547097 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 | |
| SCHEMBL7543573 | 1.00 | CYP1A2 (0.83) | CYP1A2PAOXDGKAALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114404424-A | A pharmaceutical composition for treating alopecia, and its preparation method | 硬核医药科技(上海)有限公司 | 2022-04-29 | — | — | CN | claimed |
| CN-108794358-B | Substituted benzenesulfonyl compounds and application thereof in preparing medicines | 中国人民解放军第二军医大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114404424-A | A pharmaceutical composition for treating alopecia, and its preparation method | 硬核医药科技(上海)有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-108794358-A | Substitution benzenesulfonyl class compound and its purposes for preparing drug | 中国人民解放军第二军医大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-101421251-B | 4,5-diphenyl-pyrimidinyl-amino substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI AVENTIS DEUTSCHLAND | 2011-10-19 | — | — | CN | disclosed |
| US-7713988-B2 | 4,5-diphenyl-pyrimidinylamino substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI-AVENTIS (FR) | 2010-05-11 | — | — | US | disclosed |
| US-20090149487-A1 | 4,5-DIPHENYL-PYRIMIDINYLAMINO SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | SANOFI-AVENTIS (FR) | 2009-06-11 | — | — | US | disclosed |
| CN-101421251-A | 4,5-diphenyl-pyrimidinyl-amino substituted carboxylic acids, method for the production and use thereof as medicaments | SANOFI AVENTIS DEUTSCHLAND (FR) | 2009-04-29 | — | — | CN | disclosed |
| US-20080167418-A1 | Method for Producing an Aqueous Polyamide Dispersion | BASF AKTIENGESELLSCHAFT (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080132674-A1 | Method for the Production of an Aqueous Polymer Dispersion | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-05 | — | — | US | disclosed |
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3957607-A | Process for the preparation of lipide soluble complexes of cations, application of the process and use of the complexes | W. MOLLER GLASBLASEREI (CH) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149487-A1 | 4,5-DIPHENYL-PYRIMIDINYLAMINO SUBSTITUTED CARBOXYLIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF AS MEDICAMENTS | GPR119, DPP4, SLC5A1 | CYP1A2 1216/4885PAOX 119/4885DGKA 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.