Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254157 | 0.86 | NR3C1 (0.57) | NR3C1DRD4DRD2L3MBTL1ALDH1A1 | |
| SCHEMBL7252247 | 0.85 | NR3C1 (0.66) | NR3C1ABL1RIN1L3MBTL1ALDH1A1 | |
| SCHEMBL7252910 | 0.84 | NR3C1 (0.63) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL7256747 | 0.83 | NR3C1 (0.62) | NR3C1ALDH1A1KDM4EGAANPC1 | |
| SCHEMBL5630623 | 0.82 | NR3C1 (0.85) | NR3C1ABL1RIN1ALDH1A1KDM4E | |
| SCHEMBL7251172 | 0.78 | NR3C1 (0.67) | NR3C1L3MBTL1 | |
| SCHEMBL7257439 | 0.77 | NR3C1 (0.73) | NR3C1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL5630342 | 0.77 | NR3C1 (0.70) | NR3C1 | |
| SCHEMBL7254627 | 0.77 | NR3C1 (0.78) | NR3C1ALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL7549312 | 0.76 | PTGDR2 (0.49) | PTGDR2CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002044120-A1 | COMPOUNDS ACTIVE AT THE GLUCOCORTICOID RECEPTOR III | KARO BIO AB (SE) | 2002-06-06 | — | — | WO | disclosed |