Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.52 |
| ▸ | PPARG | P37231 | 17/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379449 | 0.88 | FFAR1 (0.51) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL7488571 | 0.87 | PPARA (0.48) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL7546654 | 0.86 | PPARA (0.47) | PPARAPPARGFFAR1 | |
| SCHEMBL7488575 | 0.85 | FFAR1 (0.47) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5380963 | 0.85 | FFAR1 (0.54) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5379443 | 0.85 | PPARA (0.55) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL7540590 | 0.84 | RAB9A (0.43) | PPARAPPARGFFAR1 | |
| SCHEMBL7547501 | 0.84 | PPARA (0.49) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5380800 | 0.83 | PPARA (0.53) | PPARAPPARGFFAR1PPARD | |
| SCHEMBL5378969 | 0.83 | FFAR1 (0.54) | PPARAPPARGFFAR1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |