Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6447459 | 0.94 | SLC6A2 (0.37) | KCNH2CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL6941803 | 0.86 | — | — | |
| SCHEMBL6941808 | 0.86 | — | — | |
| SCHEMBL6941178 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL25367388 | 0.84 | NCF1 (0.43) | CHRM2CHRM1HRH3CHRM3SLC6A3 | |
| SCHEMBL6949366 | 0.82 | — | — | |
| SCHEMBL734075 | 0.82 | — | — | |
| SCHEMBL6949372 | 0.82 | — | — | |
| SCHEMBL23707762 | 0.80 | DRD1 (0.39) | KCNH2CHRM2ADRA2ACHRM1DRD1 | |
| Hydrochloric Acid SCHEMBL1896733 | 0.80 | SMN1; SMN2 (0.40) | KCNH2CHRM2ADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850953-B1 | Polymers, elastomeric compounds, and products thereof, terminated with amine compounds containing side-chain organohalide reactive moieties | BRIDGESTONE CORP (JP) | 2002-06-12 | — | — | EP | claimed |
| US-5916976-A | Polymers, elastomeric compounds, and products thereof, terminated with novel amine compounds containing side-chain organohalide reactive moieties | BRIDGESTONE CORPORATION (JP) | 1999-06-29 | — | — | US | claimed |
| EP-0850953-A1 | Polymers, elastomeric compounds, and products thereof, terminated with novel amine compounds containing side-chain organohalide reactive moieties | Bridgestone Corporation (JP) | 1998-07-01 | — | — | EP | claimed |
| US-5736617-A | LIVING END IS REACTED WITH CYCLIC AMINE CONTAINING ORGANOHALIDE SIDE CHAIN | BRIDGESTONE CORPORATION (JP) | 1998-04-07 | — | — | US | claimed |
| US-4405623-A | HYPOTENSIVE AGENTS, VASODILATORS | MASAYUKI ISHIKAWA (JP) | 1983-09-20 | — | — | US | disclosed |
| EP-0040793-A1 | Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof | Ishikawa, Masayuki (JP) | 1981-12-02 | — | — | EP | disclosed |