Etocarlide

Etocarlide

SCHEMBL7547567

CCOc1ccc(NC(=S)Nc2ccc(OCC)cc2)cc1.CC[N+](C)(C)C

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.83
GAA P10253 5/20 0.73
L3MBTL1 Q9Y468 1/20 0.66
ALDH1A1 P00352 7/20 0.61
KDM4E B2RXH2 2/20 0.61
LMNA P02545 4/20 0.60
KMT2A Q03164 5/20 0.58
MEN1 O00255 3/20 0.58
POLB P06746 2/20 0.58
HTT P42858 2/20 0.58
NSD2 O96028 1/20 0.58
HPGD P15428 1/20 0.58
BLM P54132 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
MPI P34949 1/20 0.57
CYP1A2 P05177 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etocarlide SCHEMBL2856983 0.93 MAPT (0.89) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL120610 0.93 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL1698730 0.93 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL4664310 0.91 MAPT (0.93) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL5556076 0.91 MAPT (0.93) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL103618 0.91 MAPT (1.00) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL9263 0.91 MAPT (1.00) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL2863505 0.90 MAPT (0.83) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL21694441 0.90 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL938885 0.90 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667366-B1 Process for the production of aromatic polycarbonate TEIJIN LTD (JP) 2002-06-26 EP disclosed
US-5516878-A CATALYTIC ESTER INTERCHANGE USING AN ALKALI METAL SALT OF AN ATE-COMPLEX OF A METAL SELECTED FROM SILICON, GERMANIUM, TIN, OR LEAD TEIJIN LIMITED (JP) 1996-05-14 US disclosed
EP-0667366-A2 Process for the production of aromatic polycarbonate TEIJIN LIMITED (JP) 1995-08-16 EP disclosed