Etocarlide

Etocarlide

SCHEMBL2863505

CCOc1ccc(NC(=S)Nc2ccc(OCC)cc2)cc1.CC[N+](CC)(CC)CC

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.83
GAA P10253 5/20 0.73
L3MBTL1 Q9Y468 1/20 0.66
ALDH1A1 P00352 8/20 0.61
KDM4E B2RXH2 2/20 0.61
LMNA P02545 5/20 0.60
KMT2A Q03164 5/20 0.58
MEN1 O00255 3/20 0.58
HTT P42858 3/20 0.58
POLB P06746 2/20 0.58
HPGD P15428 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
NSD2 O96028 1/20 0.58
BLM P54132 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
MPI P34949 1/20 0.57
CYP1A2 P05177 1/20 0.56
TDP1 Q9NUW8 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etocarlide SCHEMBL1698730 0.93 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL11416946 0.92 MAPT (0.76) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL103618 0.91 MAPT (1.00) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL9263 0.91 MAPT (1.00) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL7547567 0.90 MAPT (0.83) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL2856983 0.90 MAPT (0.89) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL20447982 0.90 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL20658914 0.90 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL120610 0.90 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E
Etocarlide SCHEMBL21694441 0.90 MAPT (0.96) MAPTGAAL3MBTL1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3330311-B1 STORAGE STABLE 1K-POLYURETHANE-PREPREGS AND MOULDED ARTICLE MADE FROM SAME ON THE BASIS OF A POLYURETHANE COMPOSITION EVONIK OPERATIONS GMBH (DE) 2021-05-05 EP claimed
US-10626236-B2 Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom EVONIK OPERATIONS GMBH (DE) 2020-04-21 US claimed
US-20180155515-A1 STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM EVONIK OPERATIONS GMBH (DE) 2018-06-07 US claimed
US-10793664-B2 Process for preparing trimers and/or oligomers of diisocyanates EVONIK OPERATIONS GMBH (DE) 2020-10-06 US disclosed
US-10626236-B2 Storage-stable one-component polyurethane prepregs and shaped bodies composed of polyurethane composition that have been produced therefrom EVONIK OPERATIONS GMBH (DE) 2020-04-21 US disclosed
US-10336856-B2 Alkoxysilane- and allophanate-functionalized coating materials EVONIK DEGUSSA GMBH (DE) 2019-07-02 US disclosed
US-20180327538-A1 PROCESS FOR PREPARING TRIMERS AND/OR OLIGOMERS OF DIISOCYANATES EVONIK OPERATIONS GMBH (DE) 2018-11-15 US disclosed
US-20180312713-A1 Coating compositions comprising monoallophanates based on alkoxysilane alkyl isocyanates EVONIK DEGUSSA GMBH (DE) 2018-11-01 US disclosed
US-10093826-B2 Alkoxysilane-functionalized allophanate-containing coating compositions EVONIK DEGUSSA GMBH (DE) 2018-10-09 US disclosed
US-20180155515-A1 STORAGE-STABLE ONE-COMPONENT POLYURETHANE PREPREGS AND SHAPED BODIES COMPOSED OF POLYURETHANE COMPOSITION THAT HAVE BEEN PRODUCED THEREFROM EVONIK OPERATIONS GMBH (DE) 2018-06-07 US disclosed
US-9902095-B2 Production of fibre composite component part based on steel and polyurethane EVONIK DEGUSSA GMBH (DE) 2018-02-27 US disclosed
US-6140272-A HERBICIDES; PREPARING BY ACYLATING A 1,3-SUBSTITUTED-5-HYDROXY-PYRAZOLE WITH AN ACTIVATED BENZOIC ACID DERIVATIVE AND REARRANGING THE ACYLATION PRODUCT, AND OPTIONALLY FURTHER REACTING BASF AKTIENGESELLSCHAFT (DE) 2000-10-31 US disclosed
US-5516878-A CATALYTIC ESTER INTERCHANGE USING AN ALKALI METAL SALT OF AN ATE-COMPLEX OF A METAL SELECTED FROM SILICON, GERMANIUM, TIN, OR LEAD TEIJIN LIMITED (JP) 1996-05-14 US disclosed
EP-0335274-B1 Formation of nitrophenyl ethers from polyols and nitroanisoles DOW CHEMICAL CO (US) 1996-03-13 EP disclosed
EP-0667366-A2 Process for the production of aromatic polycarbonate TEIJIN LIMITED (JP) 1995-08-16 EP disclosed
US-4960950-A Formation of nitrophenyl ethers from polyols and nitroanisoles THE DOW CHEMICAL COMPANY (US) 1990-10-02 US disclosed
US-4209643-A Preparation of acetals ETHYL CORPORATION (US) 1980-06-24 US disclosed
US-4033860-A Mercaptan conversion process UOP INC. (US) 1977-07-05 US disclosed
US-4032686-A ARTICLES COATED WITH A CURED COMPOSITION OF HYDROXY(POLYALKYLENECARBONYLOXY)ALKYLENEOXAZOLIDINE AND A POLYISOCYANATE ROHM AND HAAS COMPANY (US) 1977-06-28 US disclosed
US-4024117-A HYDROXY-ALKYLENE-OXAZOLIDINE, ISOCYANATE ROHM AND HAAS COMPANY (US) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10336856-B2 Alkoxysilane- and allophanate-functionalized coating materials DDAH1, OR10J3, AP3S1 MAPT 3932/4885GAA 4714/4885L3MBTL1 1891/4885
US-10093826-B2 Alkoxysilane-functionalized allophanate-containing coating compositions DDAH1, OR10J3, AP3S1 MAPT 3345/4885GAA 4395/4885L3MBTL1 2704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.