Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 8/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.46 |
| ▸ | F11 | P03951 | 11/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7547772 | 1.00 | PLG (0.48) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7542904 | 0.99 | PLG (0.48) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7542912 | 0.99 | PLG (0.48) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL10419583 | 0.92 | PLG (0.48) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL10419577 | 0.92 | PLG (0.48) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL7540234 | 0.84 | PLG (0.61) | PLGKLKB1PLAUPRSS1PRSS2 | |
| SCHEMBL7540226 | 0.84 | PLG (0.61) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7275801 | 0.84 | PLG (0.60) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7545755 | 0.84 | PLG (0.60) | PLGKLKB1PLAUPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7442398 | 0.83 | PLG (0.53) | PLGKLKB1PLAUPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4873253-A | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1989-10-10 | — | — | US | claimed |
| EP-0284632-A1 | Phenylalanine derivative and proteinase inhibitor | Okamoto, Shosuke (JP) | 1988-10-05 | — | — | EP | claimed |