Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76904 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29418124 | 0.81 | ALDH1A1 (0.46) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4033813 | 0.80 | KMT2A (0.46) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL30485479 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| Biphenyl SCHEMBL28948287 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28372677 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| Water SCHEMBL8392319 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| Water SCHEMBL8470277 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| Hydrogen Sulfide SCHEMBL27523825 | 0.79 | ALDH1A1 (0.44) | ALDH1A1CYP2A6GRIN2DGRIN3BGRIN1 | |
| SCHEMBL26556671 | 0.78 | CYP2A6 (0.62) | ALDH1A1CYP2A6HSD17B10HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080819-A | Blends of olefin polymers and syndiotactic vinyl polymers | BOREALIS AG (AT) | 2000-06-27 | — | — | US | claimed |
| US-20230331675-A1 | AROMATIC ETHYLENE COMPOUND AND PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2023-10-19 | — | — | US | disclosed |
| US-20230331675-A1 | AROMATIC ETHYLENE COMPOUND AND PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD. (CN) | 2023-10-19 | — | — | US | disclosed |
| EP-4212511-A1 | AROMATIC ETHYLENE COMPOUND AND PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | Guangzhou Maxinovel Pharmaceuticals Co., Ltd. (CN) | 2023-07-19 | — | — | EP | disclosed |
| WO-2022052926-A1 | AROMATIC ETHYLENE COMPOUND AND PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | 广州再极医药科技有限公司 | 2022-03-17 | — | — | WO | disclosed |
| EP-1211284-A1 | Semi-finished products or moulded materials of improved toughness made from propylene polymers | Borealis GmbH (AT) | 2002-06-05 | — | — | EP | disclosed |
| US-6080819-A | Blends of olefin polymers and syndiotactic vinyl polymers | BOREALIS AG (AT) | 2000-06-27 | — | — | US | disclosed |
| EP-0884356-A2 | Blends of polyolefins and syndiotactic vinyl polymeres | PCD Polymere AG (AT) | 1998-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331675-A1 | AROMATIC ETHYLENE COMPOUND AND PREPARATION METHOD THEREFOR, AND INTERMEDIATE, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF | PDCD1, CD274, PDCD1LG2 | ALDH1A1 243/4885CYP2A6 1115/4885GRIN2D 4516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.