Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103227 | 0.89 | ADRA2A (0.65) | ADRA2AADRA1A | |
| SCHEMBL7097490 | 0.87 | ADRA2A (0.48) | ADRA2AADRA1A | |
| SCHEMBL7098265 | 0.87 | ADRA2A (0.52) | ADRA2AADRA1A | |
| SCHEMBL7098608 | 0.86 | ADRA2A (0.67) | ADRA2AADRA1A | |
| SCHEMBL7101021 | 0.85 | ADRA2A (0.50) | ADRA2AADRA1A | |
| SCHEMBL7100817 | 0.84 | ADRA2A (0.47) | ADRA2AADRA1A | |
| SCHEMBL7098638 | 0.83 | ADRA2A (0.48) | ADRA2AADRA1A | |
| SCHEMBL7099202 | 0.83 | ADRA2A (0.44) | ADRA2A | |
| SCHEMBL7103476 | 0.83 | ADRA2A (0.46) | ADRA2AADRA1A | |
| SCHEMBL7100541 | 0.82 | ADRA2A (0.47) | ADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259491-A1 | 4-IMIDAZOLE DERIVATIVES OF BENZYL AND RESTRICTED BENZYL SULFONAMIDES, SULFAMIDES, UREAS, CARBAMATES AND AMIDES AND THEIR USE AS ALPHA-1A AGONISTS | Abbott Laboratories (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001060802-A1 | 4-IMIDAZOLE DERIVATIVES OF BENZYL AND RESTRICTED BENZYL SULFONAMIDES, SULFAMIDES, UREAS, CARBAMATES, AND AMIDES AND THEIR USE AS ALPHA-1A AGONISTS | ABBOTT LABORATORIES (US) | 2001-08-23 | — | — | WO | disclosed |