⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539087 | 0.94 | — | — | |
| SCHEMBL914857 | 0.80 | — | — | |
| SCHEMBL1831137 | 0.78 | — | — | |
| SCHEMBL3938413 | 0.74 | — | — | |
| SCHEMBL916248 | 0.74 | — | — | |
| SCHEMBL3049119 | 0.72 | — | — | |
| SCHEMBL755121 | 0.72 | — | — | |
| SCHEMBL6567295 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL789662 | 0.72 | — | — | |
| SCHEMBL914585 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9018209-B2 | Compounds and methods for the treatment of viruses and cancer | YALE UNIVERSITY (US) | 2015-04-28 | — | — | US | claimed |
| EP-2046147-B1 | METHOD OF USING ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2013-05-01 | — | — | EP | claimed |
| US-20100222352-A1 | Compounds and Methods for the Treatment of Viruses and Cancer | YALE UNIVERSITY (US) | 2010-09-02 | — | — | US | claimed |
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | claimed |
| CN-118950103-A | Multilayer core-shell structure catalyst, preparation method and application thereof | 青岛科技大学 | 2024-11-15 | — | — | CN | disclosed |
| US-10640460-B2 | Substituted cyclopentyl- and cyclohexyl-derivatives useful for perfumery | GIVAUDAN SA (CH) | 2020-05-05 | — | — | US | disclosed |
| US-10640460-B2 | Substituted cyclopentyl- and cyclohexyl-derivatives useful for perfumery | GIVAUDAN SA (CH) | 2020-05-05 | — | — | US | disclosed |
| EP-3386940-B1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2019-10-16 | — | — | EP | disclosed |
| US-20180346412-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2018-12-06 | — | — | US | disclosed |
| EP-3386940-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | Givaudan S.A. (CH) | 2018-10-17 | — | — | EP | disclosed |
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
| WO-2017097884-A1 | SUBSTITUTED CYCLOPENTYL- AND CYCLOHEXYL-DERIVATIVES USEFUL FOR PERFUMERY | GIVAUDAN SA (CH) | 2017-06-15 | — | — | WO | disclosed |
| US-20070097469-A1 | Methods for making holographic data storage articles | GENERAL ELECTRIC COMPANY (US) | 2007-05-03 | — | — | US | disclosed |
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |
| US-20070021454-A1 | Spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease | MERCK SHARP & DOHME LLC | 2007-01-25 | — | — | US | disclosed |
| WO-2007011833-A2 | SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | MERCK & CO., INC. (US) | 2007-01-25 | — | — | WO | disclosed |
| EP-1381593-A2 | (2-HYDROXY)ETHYL-THIOUREAS USEFUL AS MODULATORS OF ALPHA2B ADRENERGIC RECEPTORS | Allergan, Inc. (US) | 2004-01-21 | — | — | EP | disclosed |
| US-6534542-B2 | For alleviating chronic pain and allodynia and have no or only minimal cardivascular and/or sedatory activity | ALLERGEN SALES, INC. | 2003-03-18 | — | — | US | disclosed |
| US-20020161051-A1 | (2-hydroxy)ethyl-thioureas useful as modulators of alpha2B adrenergic receptors | ALLERGAN SALES, INC. | 2002-10-31 | — | — | US | disclosed |
| WO-2002068384-A2 | (2-HYDROXY)ETHYL-THIOUREAS USEFUL AS MODULATORS OF ALPHA2B ADRENERGIC RECEPTORS | ALLERGAN, INC. (US) | 2002-09-06 | — | — | WO | disclosed |