SCHEMBL7548784

SCHEMBL7548784

COC(=O)Nc1ccc(O)cc1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.59
SMN1; SMN2 Q16637 4/20 0.53
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 3/20 0.49
PKM P14618 2/20 0.49
CYTH2 Q99418 1/20 0.45
ALDH1A1 P00352 3/20 0.45
HTT P42858 3/20 0.45
GLA P06280 1/20 0.45
THRB P10828 1/20 0.45
LMNA P02545 3/20 0.44
GAA P10253 2/20 0.44
POLB P06746 1/20 0.44
GFER P55789 1/20 0.44
TAS1R3 Q7RTX0 1/20 0.43
TAS1R1 Q7RTX1 1/20 0.43
TAS1R2 Q8TE23 1/20 0.43
EGFR P00533 1/20 0.43
KDR P35968 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2092869 0.85 HPGD (0.75) HPGDSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL11653362 0.83 HPGD (0.61) HPGDSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL29958958 0.83 SMN1; SMN2 (0.47) HPGDSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL2770751 0.83 SMN1; SMN2 (0.47) HPGDSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL4830911 0.82 MAPT (0.49) HPGDSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL21323871 0.81 HPGD (0.59) HPGDSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL31198186 0.81 ALDH1A1 (0.57) HPGDMEN1KMT2AMAPTCYTH2
SCHEMBL3324996 0.81 ALDH1A1 (0.57) HPGDMEN1KMT2AMAPTCYTH2
SCHEMBL11653044 0.80 RAB9A (0.60) HPGDSMN1; SMN2MEN1KMT2AMAPT
SCHEMBL2095501 0.80 SMN1; SMN2 (0.59) HPGDSMN1; SMN2MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11147866-A None JP disclosed
EP-0795550-B1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO CO (JP) 2002-06-05 EP disclosed
JP-H11147866-A AMINOPHENOL DERIVATIVE SANKYO CO LTD 1999-06-02 JP disclosed
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed
EP-0795550-A1 Aniline derivatives having herbicidal activity their preparation and their use SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed