Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7376337 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL2680220 | 0.95 | CYP1A2 (0.50) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL16744188 | 0.91 | CYP1A2 (0.46) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL17403329 | 0.91 | IGF1R (0.53) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL11395796 | 0.88 | IGF1R (0.52) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL7547399 | 0.87 | CYP1A2 (0.56) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL7434377 | 0.85 | CYP1A2 (0.59) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL6546754 | 0.82 | IGF1R (0.64) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL6546878 | 0.82 | CYP1A2 (0.62) | CYP1A2CYP2A6TAAR1ALOX15IGF1R | |
| SCHEMBL28184336 | 0.79 | IGF1R (0.61) | CYP1A2CYP2A6TAAR1ALOX15IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482990-B1 | Prostaglandin E analogues | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-1211241-A1 | PROSTAGLANDIN E ANALOGUES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-06-05 | — | — | EP | disclosed |